Peptipedia / Research subject

Incretin receptors

Research into GLP-1, GIP and glucagon receptor biology and signaling.

Explore the papers.

14 publications

2025 DecThe Journal of investigative dermatology
GLP-1 Receptor Agonists as Emerging Modulators of Inflammation and Angiogenesis in Chronic Cutaneous Wound Healing.
Ghebrehiwet-Kuflom J, Mehta A, Lim P et al.
PubMed · PMID 41081666Review
2025 JanAdvanced science (Weinheim, Baden-Wurttemberg, Germany)
GLP-1 Receptor Agonists Alleviate Diabetic Kidney Injury via β-Klotho-Mediated Ferroptosis Inhibition.
Tian S, Zhou S, Wu W et al.
PubMed · PMID 39630101Journal article
2024Frontiers in endocrinology
Mechanisms of action and therapeutic applications of GLP-1 and dual GIP/GLP-1 receptor agonists.
Liu QK
PubMed · PMID 39114288Review
2024 FebMolecular metabolism
Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 receptor agonism.
Nunn E, Jaiswal N, Gavin M et al.
PubMed · PMID 38218536Journal article
2023 Mar 30Cell
Negative allosteric modulation of the glucagon receptor by RAMP2.
Krishna Kumar K, O'Brien ES, Habrian CH et al.
PubMed · PMID 37001505Journal article
2022 DecPharmacological research
Glucagon-like peptide-1 (GLP-1) receptor agonists and neuroinflammation: Implications for neurodegenerative disease treatment.
Kopp KO, Glotfelty EJ, Li Y et al.
PubMed · PMID 36372278Review
2022 Aug 24International journal of molecular sciences
Anti-Inflammatory Effects of GLP-1 Receptor Activation in the Brain in Neurodegenerative Diseases.
Diz-Chaves Y, Mastoor Z, Spuch C et al.
PubMed · PMID 36076972Review
2022 Apr 14International journal of molecular sciences
The Role of Glp-1 Receptor Agonists in Insulin Resistance with Concomitant Obesity Treatment in Polycystic Ovary Syndrome.
Bednarz K, Kowalczyk K, Cwynar M et al.
PubMed · PMID 35457152Review
2022 MayPeptides
GLP-1 and GIP receptor signaling in beta cells - A review of receptor interactions and co-stimulation.
Mayendraraj A, Rosenkilde MM, Gasbjerg LS
PubMed · PMID 35065096Review
2021 NovDiabetes
GIP Receptor Agonism Attenuates GLP-1 Receptor Agonist-Induced Nausea and Emesis in Preclinical Models.
Borner T, Geisler CE, Fortin SM et al.
PubMed · PMID 34380697Journal article
2021International journal of biological sciences
GLP-1 receptor agonists (GLP-1RAs): cardiovascular actions and therapeutic potential.
Ma X, Liu Z, Ilyas I et al.
PubMed · PMID 34131405Review
2020 Nov 24Proceedings of the National Academy of Sciences of the United States of America
Structural basis for GLP-1 receptor activation by LY3502970, an orally active nonpeptide agonist.
Kawai T, Sun B, Yoshino H et al.
PubMed · PMID 33177239Journal article
2020 Sep 3JCI insight
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist.
Willard FS, Douros JD, Gabe MB et al.
PubMed · PMID 32730231Journal article
2020 Jun 2Cell metabolism
GLP-1 Receptor Signaling in Astrocytes Regulates Fatty Acid Oxidation, Mitochondrial Integrity, and Function.
Timper K, Del Río-Martín A, Cremer AL et al.
PubMed · PMID 32433922Journal article